Fady Hannah-Shmouni, MD FRCPC
Peptides Simplified
A modern introduction
About this book
Peptide medicine is having its most consequential decade since insulin was discovered. GLP-1 agonists like semaglutide and tirzepatide have moved peptides from specialist clinics into everyday conversation. With that attention has come a flood of misinformation, gray-market products, and confident claims that outrun the evidence.
Peptides Simplified is a modern introduction for the intelligent non-specialist. It explains what peptides are and how they differ from small-molecule drugs and full proteins. It walks through the peptides that already transformed medicine — insulin, GLP-1 agonists, and their relatives. Then it gives you a framework for evaluating the newer names — recovery peptides, 'longevity' compounds, cosmetic injectables — on the strength of their actual evidence.
Every chapter is written to be readable in one sitting, with the science explained from first principles and the marketing claims tested against the published literature.
What you'll learn
- What a peptide actually is — and why the line between peptide, protein, and drug matters for safety and regulation
- How insulin became the first therapeutic peptide and what its history teaches about the current boom
- How GLP-1 receptor agonists work, what the trial data shows, and what the honest open questions are
- A framework for evaluating any peptide claim: mechanism plausibility, evidence tier, and regulatory status
- The gray market explained: compounding, research chemicals, and why purity claims deserve skepticism
- Which 'longevity' and recovery peptides have real data behind them, and which are running on anecdote
Who it's for
- Readers who keep hearing about peptides and want one clear, trustworthy primer
- Patients starting (or considering) GLP-1 therapy who want to understand the science
- Health professionals outside endocrinology who want a fast, accurate orientation
Frequently asked questions
Do I need a science background to read this?
No. The book is written for the intelligent general reader. Every technical concept is built from first principles, and chapter summaries capture the key points.
Does it cover GLP-1 drugs like Ozempic and Mounjaro?
Yes — the GLP-1 class is covered in depth: how the drugs work, what the major trials showed for weight and metabolic outcomes, side effects, and the questions that remain open.
Is this the same content as the Arabic edition?
The Arabic edition (الببتيدات: مدخل مبسط) is a translation of the same book, adapted for Arabic-speaking readers. The scientific content is identical.
What's inside
- 1Preface
- 2How to read this book
- 3Part One — The Basics
- 4Ch. 1 What peptides actually are
- 5Ch. 2 How peptides work in the body
- 6Ch. 3 A short history of peptide medicine
- 7Part Two — The Drug Landscape
- 8Ch. 4 The peptide drug classes
- 9Ch. 5 The GLP-1 revolution
- 10Ch. 6 Unapproved peptides — an honest look
- 11Part Three — Practical Pharmacology
- 12Ch. 7 Pharmacokinetics, half-life, receptors
- 13Ch. 8 How peptides are made and delivered
- 14Ch. 9 Quality, safety, and the compounding question
- 15Ch. 10 Regulation, sports, ethics, and what's next
- 16Part Four — Using Peptides Safely
- 17Ch. 11 How to evaluate what you're being sold
- 18Ch. 12 Practical self-administration of approved peptide drugs
- 19Part Five — The Bigger Picture
- 20Ch. 13 Economics and peptides
- 21Glossary
- 22References
- 23About the author
Preview
Free sampleThis is a free preview. Purchase the book above to download the full PDF.
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