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Growth Hormone — Somatropin, Long-Acting Analogues and Secretagogues: The Evidence, the Dosing, and the Law

Fady Hannah-Shmouni, MD, FRCPC, ABIM

Growth Hormone — Somatropin, Long-Acting Analogues and Secretagogues: The Evidence, the Dosing, and the Law

A clinician’s evidence monograph · First edition · 2026

$9.00153 pages • PDF • Free sample available
A 153-page evidence-graded clinical monograph for licensed clinicians. The 2026 first edition covers the GH/IGF-1 axis, pediatric and adult diagnosis, daily somatropin and long-acting analogues, secretagogues, dosing and monitoring, evidence, international regulation, and medicolegal practice. Educational content and a reference for clinical reasoning—not medical advice for any individual.

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What's inside

  1. 1How to use this book
  2. 2Growth hormone at a glance
  3. 3Part 01 — Foundations
  4. 4Growth hormone and IGF-1: the axis
  5. 5Growth hormone across the lifespan
  6. 6Measuring GH and IGF-1
  7. 7Part 02 — Diagnosis
  8. 8Growth disorders in children
  9. 9Adult GH deficiency: causes and who to test
  10. 10Stimulation testing
  11. 11Limits of IGF-1 and GH testing
  12. 12GH excess: genetic and pituitary causes
  13. 13GH excess: diagnostic work-up
  14. 14Contraindications and who not to treat
  15. 15Part 03 — Therapy
  16. 16Daily somatropin products
  17. 17Somatropin products compared
  18. 18Long-acting GH analogues
  19. 19Once-weekly analogues compared
  20. 20Dosing by indication and titration
  21. 21GH secretagogues: oral and injectable
  22. 22Secretagogues compared
  23. 23Analogues vs secretagogues
  24. 24Monitoring, adverse effects and long-term safety
  25. 25Monitoring schedule
  26. 26Part 04 — Regulation and Practice
  27. 27International guidelines compared
  28. 28Regulation across jurisdictions
  29. 29Regulation by jurisdiction
  30. 30GH, anti-ageing claims and biological age
  31. 31Misuse, medicolegal duties and consent
  32. 32Special populations and putting it together
  33. 33About the author
  34. 34About this monograph

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